The Aerolysin-Like Toxin Family of Cytolytic, Pore-Forming Toxins~!2009-08-20~!2009-09-17~!2010-03-09~!

The Aerolysin-Like Toxin Family of Cytolytic, Pore-Forming Toxins

Pore-forming toxins (PFTs) represent the largest known group of bacterial protein toxins to date. Membrane insertion and subsequent pore-formation occurs after initial binding to cell-surface receptor and oligomerization. Aerolysin, a toxin produced by the Gram-negative bacterium Aeromonas hydrophila and related species, belongs to the PFT group and shares a common mechanism of action involving...

Cumyluron 09/08/09

REVUE 08/09.book

As nitrogen metabolism is exacerbated during diabetes mellitus or/and pregnancy, and because arginase catalyses the arginine hydrolysis into ornithine and urea, this enzyme activity as well as the ornithine content were investigated in tissues (liver, kidney and brain) from pregnant or non pregnant streptozotocin (STZ) diabetic rats, dietary supplemented or not with antioxidant vitamins (C and ...

Sensitivity of polarized epithelial cells to the pore-forming toxin aerolysin.

Aerolysin is one of the major virulence factors produced by Aeromonas hydrophila, a human pathogen that produces deep wound infection and gastroenteritis. The toxin interacts with target mammalian cells by binding to the glycan core of glycosylphosphatidyl inositol (GPI)-anchored proteins and subsequently forms a pore in the plasma membrane. Since epithelial cells of the intestine are the prima...

REVUE 08/09.book

The retention of foetal membranes (RFM) is supposed to be related to oxidative stress which can be evaluated through indirect and direct parameters, among others, total antioxidant capacity (TAC) and lipid peroxidation intensity (LPI). Placental samples (maternal and foetal parts) were collected from Holstein-Friesian healthy cows immediately after caesarean section (n = 13, group A) at time or...